Abstract

Recent studies have underscored the unique biological activities of oligosaccharides derived from edible-medicinal mushrooms, highlighting their superiority over polysaccharides due to their simpler structures and increased bioavailability. Investigating the structure-activity relationship of oligosaccharides could help overcome the technical challenges associated with the intricate structural analysis of polysaccharides. Despite numerous studies on oligosaccharide compounds, our understanding of oligosaccharides from edible-medicinal mushrooms remains limited. This review aims to outline current trends in oligosaccharide research and clarify the health-promoting characteristics of oligosaccharides derived from edible-medicinal mushrooms. It offers a comprehensive analysis of the glycan chain structures and biological activities of oligosaccharides and advocates for the establishment of an oligosaccharide compound library specific to edible-medicinal mushrooms. This approach might expedite the high-throughput screening of active oligosaccharides, thus stimulating the development of related health foods and products, and facilitating industrial advancement.

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