Abstract
This comprehensive review scrutinizes the progress and challenges in the field of autoimmunity, with a particular focus on the United States. It assesses the intricate roles of immunosuppressive medications, their benefits, and their significant drawbacks, such as increased susceptibility to infections. Emphasizing the need for further research, the paper highlights the criticality of a deeper understanding of the immune system's response to both endogenous and exogenous substances to devise more targeted treatments. Current trends post-COVID-19 and the heightened risks among women due to genetic predispositions are also explored, underscoring the urgency for advancements in autoimmune research.
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