Abstract

Gas chromatography (GC) is a versatile analytical technique with a rich history of advancements in quantitative analysis. This review explores the enduring relevance of GC, focusing on principles and instrumentation. GC’s ability to separate and quantify volatile compounds has solidified its place in environmental analysis, pharmaceuticals, food chemistry, and forensic science. With advanced instrumentation, sample preparation techniques, and quality control, GC continues to meet the demands of modern research. Recent innovations, including miniaturization, hyphenated techniques, and automation, enhance its precision and accessibility. This review highlights the challenges and prospects for GC in a changing analytical landscape, emphasizing sustainability and efficiency. Gas chromatography remains an indispensable tool for researchers, offering continued innovation and steadfast performance in quantitative analysis. Keywords: Sensitivity, Selectivity, Stationary Phase, Carrier Gas, Injector, Detectors, Column, Sample Introduction.

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