Abstract
4-Hydroxynonenal (HNE) is an important modification with great biological characterization and clinical significance. The low-abundance HNE modified proteins need to be enriched before mass spectrometry analysis. Here we summarize the current research state and theory of enrichment methods (four methods: immunoaffinity enrichment, biotin-avidin enrichment, fluorous solid-phase extraction, solid-phase hydrazide enrichment) for HNE modified proteomes, and describe the advantages and disadvantages of each method. Finally, we discuss the search trends of the HNE modified proteins in future.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
