Advanced Sensor Materials for Drug Analysis

Abstract

<div>Nanomaterials play an important role in the fabrication of many devices and</div><div>modified materials, due to their unique properties, such as large surface area/volume</div><div>ratio, conductivity and high mechanical strength. In the present chapter, the</div><div>applicability of nanomaterials in drug analysis is well investigated. The recent trends in</div><div>the development of the electrochemical sensor platforms based on state-of-the-art</div><div>nanomaterials such as metal nanoparticles, metal oxide nanoparticles, carbon</div><div>nanomaterials, conducting polymer and nanocomposites are discussed. The unique</div><div>synthetic approaches, properties, integration, strategies, selected sensing applications</div><div>and future prospects of these nanostructured materials for the design of advanced</div><div>sensor platforms are also highlighted. Various kinds of functional nanocomposites have</div><div>led to the enhancement in voltammetric response due to drug - nanomaterials</div><div>interaction at the modified electrode surface. So, different mechanisms for the</div><div>extraordinary and unique electrocatalytic activities of such nanomaterials will be</div><div>highlighted. Potential applications of electrochemical sensor platforms based on</div><div>advanced functional nanomaterials for drug analysis are presented. High sensitivity and</div><div>selectivity, fast response, and excellent durability in biological media are all critical</div><div>aspects which will also be addressed. It is expected that the chemically modified</div><div>electrodes with various nanomaterials can be easily miniaturized and used as wearable,</div><div>portable and user friendly devices. This will pave the way for in-vivo onsite real</div><div>monitoring of single as well as multi-component pharmaceutical compounds. The</div><div>significant development of the nanomaterials based electrochemical sensor platforms is</div><div>giving rise to a new impetus of generating novel technologies for securing human and</div><div>environmental safety. </div>