Abstract
肺癌是我国发病率及死亡率最高的恶性肿瘤，其早期诊断和监测复发与转移，对提高肺癌5年生存率尤为重要。循环肿瘤细胞（circulating tumor cells, CTCs）作为一种代表原发肿瘤的“液态活检标本”，有助于实时、无创性地进行组织学鉴定。CTCs检测有助于肺癌早期诊断、监测肿瘤复发与转移、判定疗效和预后，而且可能成为检测临床分子、分析耐药分子机制及解决肿瘤异质性的一种手段。本文就近年来CTCs在肺癌领域的研究进展进行综述。
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