Abstract

Introduction. Ovarian dysgerminoma is a rare malignant ovarian germ cell tumor with its peak incidence in young women. Abdominal pain, abdominal distention, and the presence of a palpable mass are common symptoms at presentation. Depending on the FIGO stage at presentation the prognosis of dysgerminomas after surgical treatment, adjuvant chemotherapy, and radiotherapy is promising. Case Presentation. A 7-year-old girl was presented at our clinic with abdominal pain in all abdominal quadrants. Later the pain localized in the region of her right ovary. CT scan revealed a massive formation which was connected to her right ovary. Conclusion. Although malignant ovarian germ cell tumours are rare in children, physicians must always consider the possibility of MOGT-occurrences. The clinical symptoms might not be specific: abdominal pain, abdominal distention, nausea, and vomiting. In order to make a correct diagnosis the patients should undergo a complete clinical examination including radiological scans. Initial management is frequently surgery, followed by adjuvant chemotherapy and radiotherapy. Although disgerminoma is malignant tumor, the prognosis is promising.

Highlights

  • Ovarian dysgerminoma is a rare malignant ovarian germ cell tumor with its peak incidence in young women

  • Preoperative elevation of tumor markers is significantly related to poor prognosis for progression-free survival (PFS) [4]

  • We report the case of a 7-year-old Albanian girl who was presented with abdominal pain and a palpable mass in the region of her right ovary

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Summary

Introduction

Dysgerminoma is a rare malignant ovarian germ cell tumor (MOGT) which is highly malignant and has its peak incidence in young women. One-third of all dysgerminomas show KIT mutations and these are associated with advanced stage at presentation [1]. The patients present with abdominal pain, abdominal distention, and presence of a palpable mass, reduced appetite, vomiting, and nausea as well as ovarian torsion [2, 3]. Fertility-preservation surgery is often possible [3] and the overall survival is 92.4% [4]. Preoperative elevation of tumor markers is significantly related to poor prognosis for progression-free survival (PFS) [4]. Dysgerminomas reveal in 28% of cases presence of lymph node metastasis, which is significantly associated with lower 5-year survival (82.8%) [5]. Older patients were more likely to be diagnosed at an advanced stage [6]

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