Abstract
Background: Once patients have a diagnosis of localization related epilepsy (LRE), it is critical to further classify those patients into lesional or non-lesional for treatment and prognostic reasons. The cornerstone of lesion detection in chronic epilepsy is structural imaging, mainly magnetic resonance imaging. Molecular & Metabolic information from Diffusion weighted MRI & magnetic resonance spectroscopy (MRS) might serve as an additional or as a surrogate marker for the epileptogenic lesion. Methods: 70 patients presented to Aljahra general hospital, Jahra city, Kuwait and were referred to radiology department for MRI study patients represented spectrum for different causes of epilepsy & different age groups All patients was scanned using Semens Aera 1.5 tesla & skyra 3 tesla magnets by conventional MRI ((T1WI, T2WI, FALIR), Diffusion weight images ( DWI/ADC) sequences & MRS were done for patients with SOL, suspected vascular or inflammatory causes. The patients with fits with no MRI signal or structural abnormality are excluded from this study. Results: DWI & MRS can provide additional diagnostic information that may facilitate and support the final diagnosis, especially if clinical symptoms are inconclusive. While conventional imaging provided only anatomical information, Conclusion: Diffusion weighted images (DWI) & SWI with conventional MRI increased accuracy of diagnosis of lesional epilepsy.
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