Abstract
A novel method for the rapid prototyping of personalized inflatable left atrial appendage occluders, suitable for minimally invasive delivery, is demonstrated. The method allows for the design, fabrication, and quantitative testing of implants based on an individual's computed tomography (CT) scan. The performance of a left atrial appendage occluder by characterizing its ability to anchor, prevent leaks, and not obstruct the left atrium is reported on. The design of the occluder by varying features such as size, inflation fluids, and surface patterns is optimized. The implant, and its delivery via a minimally invasive catheter, is demonstrated in a 3D‐printed left atrial model. Herein, the way for leveraging advanced manufacturing and imaging technologies for the development of personalized intracardiac implants for transcatheter delivery is described.
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