Abstract

Whipple's disease is a rare multisystemic infection caused by the bacterium Tropheryma whipplei. Endoscopic findings are mostly limited and include pale yellow, shaggy mucosa with intermittent, superficial, and erythematous eroded patches of the duodenum. This video demonstrates the concept of advanced endoscopic imaging of Whipple's disease using confocal laser endomicroscopy. In this setting, endomicroscopy was able to visualize disease-specific histological changes in vivo. This article is part of an expert video encyclopedia.

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