Abstract
Introduction: The aging process uniquely challenges facial aesthetics by inherent variable soft-tissue and structural remodeling. Rejuvenation of the aging face by autologous fat transfer (AFT) enriched with adipose-derived stem cells (ADSCs) remains a treatment option for volume restoration and contour deficiencies, establishing facial harmony and beauty. Successful outcomes incorporate artistic principles and sound fat-grafting techniques. Materials and Methods: The author presents a review of current scientific PubMed literature and sculptural resources on facial aging, aesthetics, and autologous fat and stem cell grafting and describes advanced fat-grafting techniques for facial rejuvenation. Results: Improved clinical fat graft survivability and aesthetic outcomes have been observed in 50 patients treated by the proposed techniques of autologous fat graft and stem cell recipient bed preparation administered by sculptural fat transplantation. Conclusions: Sculptural fat restoration integrated with AFT and selective ADSC seeding is an important key to facial rejuvenation, producing aesthetically pleasing and lasting results.
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