Abstract
IntroductionAdenoid cystic carcinoma is a malignant epithelial neoplasm derived from the salivary glands. Primary adenoid cystic carcinoma of the cervix is extremely rare, accounting for less than 1% of all cervical carcinomas. In this paper we report a case of primary adenoid cystic carcinoma and a review of the related literature.Case presentationA 68 year-old woman was admitted with signs and symptoms suggestive of a cervical cancer. The radiological and pathological investigations confirmed the diagnostic of primary adenoid cystic carcinoma of the cervix at Stage IIIB according to the International Federation of Gynaecology and Obstetrics classification. The patient was managed successfully by concurrent chemo-radiotherapy.ConclusionThe optimal management of adenoid cystic carcinoma cannot be established for certain. From our case and from the literature, it appears that combined treatment (surgery, radiotherapy, and chemotherapy) is necessary for achieving a long-term remission. Concurrent chemo-radiotherapy appears to be a logical option for locally advanced disease.
Highlights
Introduction: Adenoid cystic carcinoma is a malignant epithelial neoplasm derived from the salivary glands
The radiological and pathological investigations confirmed the diagnostic of primary adenoid cystic carcinoma of the cervix at Stage IIIB according to the International Federation of Gynaecology and Obstetrics classification
From our case and from the literature, it appears that combined treatment is necessary for achieving a long-term remission
Summary
Adenoid cystic carcinoma (ACC) is a malignant epithelial neoplasm derived from the salivary glands and can occur in a variety of other sites. It is characterized by slow growth and high rate of local recurrence. The patient was staged IIIB according to the FIGO classification (classification systems established by the International Federation of Gynaecology and Obstetrics for the staging of gynaecological cancers). She was managed with concurrent chemotherapy and photon (25MV) external-beam radiotherapy (RT). She is continuously followed by our group up to now
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