Abstract

Spinal cord injury (SCI) has remained a challenging area for scientists. In recent years, with the development and research of endogenous neural stem cells in the central nervous system, the use of endogenous neural stem cells (ENSCs) in the treatment of brain diseases has made some progress, but almost no activation of spinal cord ENSCs to repair spinal cord function recovery report. To identify the identity and distribution of ENSCs in the adult spinal cord, to analyze their fate mechanism, to find its active intervention target, has become a new idea for the treatment of spinal cord injury. Recent studies have shown that the ependymal cells of the spinal cord have the potential of neural stem cells, the current research progress is summarized. Key words: Ependymal cell; Spinal cord injury; Endogenous neural stem cell; Niche; Neurogenesis; Wound repair

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