Abstract

Manganese superoxide dismutase (MnSOD) is the major antioxidant enzyme in eukaryoeytes. It is a new potent type of tumor-suppressor gene. It can inhibit the growth of tumor, but its expression is abnormal in tumor. This review briefly highlights recent advance about the role of tumor suppressed and update of gene therapy targeted on MnSOD. Key words: Manganese superoxide dismutase; Tumor-suppressor gene

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