Abstract
Introduction: Primary embryonal rhabdomyosarcoma of prostate (ERMP) is an extremely rare pathological and clinical entity in adults. It’s characterized by extensive loco-regional spread and a tendency to metastasize by blood stream and regional lymphatics. In adult patients, data available on the management of ERMP are limited and mostly derived from the pediatric clinical trials on rhabdomyosarcoma. Case Report: We report a case of group III ERMP approached by initial surgery followed by the administration of three courses of vincristine, doxorubicin and Cyclophosphamide regimen. The patient succumbed to disease complications three months after the original diagnosis. Conclusion: The most appropriate therapeutic approach for adults with ERMP remains questionable. Further studies are needed to improve the understanding of biological behavior of ERMP in adults and to define the best therapeutic strategy in locally advanced disease.
Highlights
Primary embryonal rhabdomyosarcoma of prostate (ERMP) is an extremely rare pathological and clinical entity in adults
The present study reports a case of an adult patient
The histogenesis of embryonal rhabdomyosarcomas is curious because they have a propensity to arise in tissues, such as the middle ear, bile duct, bladder, and prostate, that are devoid of skeletal muscle
Summary
Prostate rhabdomyosarcoma is a highly malignant tumor predominantly found in children. In adults, this tumor is extremely rare and clinical experience is limited to case reports. The present study reports a case of an adult patient. How to cite this paper: Amaadour, L., et al (2014) Adult Primary Prostate Embryonal Rhabdomyosarcoma: Report of a Case and Revue of Literature.
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