Abstract

Background: There is a need for analytical tools predicting the risk of periodontitis. The purpose of this study was to estimate and evaluate a risk score for prediction of periodontitis. Materials and methods: This case-cohort study included a random sample of 155 cases (with periodontitis) and 175 controls (randomly sampled from the study population at baseline) that were followed for 3-year. A logistic regression model was used with estimation of the risk ratio (RR) for each potential predictor. Results: The risk model included the predictors “age > 53 years” (RR = 0.53), “smoking” (RR = 2.9), “gingivitis at baseline” (RR = 3.1), “subgingival calculus at baseline” (RR = 1.9), “history of periodontitis” (RR = 2.3), and “less than 2 observations in the first year of follow-up” (RR = 3.7). Patients were distributed into three risk groups based on the preanalysis risk: low risk, moderate risk, and high risk. The risk score discrimination (95% confidence interval (CI)) was 0.75 (0.70; 0.80) (p < 0.001, C-statistic). Conclusions: The risk score estimated in the present study enabled to identify patients at higher risk of experiencing periodontitis and may be considered a useful tool for both clinicians and patients.

Highlights

  • IntroductionAccording to the global burden or oral disease report of 2005, the prevalence of periodontitis among adults is between 5 and 20% worldwide [1]

  • Periodontitis represents one of the most prevalent disease worldwide

  • The present study estimated a risk score for prediction of periodontitis retrieved from a risk algorithm indicating a high degree of significance (p < 0.001 for the goodness of fit)

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Summary

Introduction

According to the global burden or oral disease report of 2005, the prevalence of periodontitis among adults is between 5 and 20% worldwide [1]. This prevalence estimation was further consolidated in a systematic review and meta-regression, estimating a global age-standardized prevalence of severe periodontitis in the year 2010 at 11.2% (95% uncertainty interval: 10.5–12.0%) [2]. Analyzing the average percentages of maximum Community Periodontal Index (CPI) scores among 35–44-year-olds worldwide, indicates that the symptoms of periodontal disease (CPI = 3 or 4) are highly prevalent among adults of all regions, ranging between 37% and 63% [1]. Conclusions: The risk score estimated in the present study enabled to identify patients at higher risk of experiencing periodontitis and may be considered a useful tool for both clinicians and patients

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