Adult Onset Still’s Disease Presented with Acute Encephalitis

Abstract

Adult-onset Still’s disease (AOSD) is a systemic inflammatory disorder of unknown pathophysiology. It is characterized by daily spiking fever, arthritis, and evanescence accompanied with elevated serum ferritin level. Neurological manifestations in AOSD are rare and may include aseptic meningitis, seizures, peripheral neuropathy, and ischemic stroke. Neurological manifestations as the initial presenting symptoms of AOSD are very rare. Here, we present a patient with AOSD who exhibited acute encephalitis as the first manifestation.