Abstract
Langerhans cell histiocytosis (LCH) of the spine involving the intervertebral disk and adjacent vertebra is rare in adults. We report a case of a 56-year-old woman with neck pain and right upper limbs numbness. Fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) showed an osteolytic bone lesion in the fourth cervical vertebra (C4) with soft-tissue mass, invading the adjacent intervertebral disc and posterior vertebral body of C3, compressing dural sac and cervical spinal cord. The lesion showed increased 18F-FDG uptake with a maximum standardized uptake value (SUVmax) of 6.75. Subsequently, the histopathologic examination confirmed the diagnosis of LCH.
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