Adult Hirchsparung’s Disease in 20 Years Old Female: Report of Case

Abstract

Hirschsparung’s Disease is a congenital disease of the colon that rare seen in adult and usually misdiagnosed or undiagnosed. And characterized by the lack of ganglion cells of the sub mucosal (Meissner) and myentric (Auerbach) neural plexuses in the affected segment of the bowel. We present a 20 years female who had absolute constipation with abdominal distention and vomiting and had history of delayed of passage of meoconum with recurrent episode of constipation since childhood that required recurrent hospital admission. The diagnosis was made upon the history and rectal biopsy that showed there's absence of ganglion cells in myentric (Auerbach) and sum-mucosal (Meissner) plexus in the distal colon which is typical to the classical form of hirschsprung’s disease. She treated firstly with sigmoid colostomy followed by pull through operation after she was returned back to hospital at 25 years old with no complication postoperatively. So Hirschsparung’s disease should be considered in the causes of recurrent constipation in any adult case.