Adult Granulosa Tumor: Case Report

Abstract

Granulosa tumors account for approximately 2-3% of ovarian tumors. They are the most frequent malignant tumors in the group of sexual cord and stromal tumors. They are mostly localized forms with a good prognosis. The main prognostic factor is the stage, with a high risk of recurrence when the tumor is of stage IB or higher. Recurrences are sometimes very late (more than 20 years after the initial treatment) and surveillance must be prolonged. We report a case of adult granulosa tumor in a 70-year-old patient, married nulligest, menopausal for 15 years, whose reason for consultation was spontaneous postmenopausal metrorrhagia associated with pelvic pain evolving for 1 year and whose pelvic imaging was in favor of a large suspicious solid-cystic formation measuring 20x12x9cm. A total hysterectomy with bilateral adnexectomy completed with multiple ascites fluid samples, epiploic and peritoneal biopsy was performed and found to be an adult granulosa tumor classified as IC1. No adjuvant treatment was proposed and the immediate evolution was favorable. Through this case we will study the clinical presentation, the characteristics, the modalities of treatment as well as the prognosis of this rare entity.