Adult Granulosa Cell Tumor Associated with Endometrial Carcinoma

Abstract

ABSTRACT Adult granulosa cell tumors account for approximately 1 and 2% of all ovarian tumors and 95% of all granulosa cell tumors. They occur more often in postmenopausal than in premenopausal women, with a peak incidence between 50 and 55 years of age. They are the most common estrogenic ovarian tumors diagnosed clinically. The typical endometrial reaction associated with functional tumors in this category is simple hyperplasia that usually exhibits some degree of precancerous atypicality. The incidence of associated endometrial carcinomas is under 5%, and most of these endometrial cancers are well-differentiated endometrioid adenocarcinomas that carry a good prognosis when detected early. We report the case of a 85-year-old woman with endometrial adenocarcinoma and adult granulose cell tumor of the ovary who presented with postmenopausal bleeding and adnexal mass. She underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy, infracolic omentectomy, and pelvic lymphadenectomy, and the specimen was submitted for histopathological examination. She had a good postoperative recovery and was discharged 5 days after treatment. The association between adult granulosa cell tumors of the ovary and endometrial carcinomas is rare. A high index of suspicion and good imaging and histopathologic analyses are important in making this diagnosis. How to cite this article Baser A, Zaidi AK, Sanghvi N. Adult Granulosa Cell Tumor Associated with Endometrial Carcinoma. J South Asian Feder Obst Gynae 2016;8(3):246-248.