Abstract
Polyphenols have potent antioxidant capacities and may reduce chronic disease risk. However, they are sensitive to pH, temperature, and light, limiting their applications. This study developed a starch nanoparticle based nanocarrier on which to load four polyphenols: (+)-catechin, (−)-epicatechin, (−)-epigallocatechin-3-gallate, and proanthocyanidins. The adsorption kinetics, adsorption isotherms, loading amount, loading efficiency, antioxidant activities, and in vitro release of the loaded polyphenols were analysed. The 2,2-diphenyl-1-picrylhydrazyl radical scavenging activity demonstrated loaded polyphenols were more stable than free polyphenols if exposed to ionic strength, heating, and ultraviolet radiation. In addition, low cytotoxicity and good biocompatibility were found as determined by methyl thiazolyl tetrazolium assay. In artificial gastric (pH 2.0) and intestinal (pH 7.0) juices, the polyphenols showed a sustained release. These findings could lead to food formulations based on SNPs as a carrier of polyphenols and other bioactive compounds.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
