Abstract
THIS communication is prompted by the finding of Urist and Deutsch1 that large doses of freeze-dried adrenocorticotrophin of mammalian origin were without effect on the blood sugar of adult cocks (Black Minorcas) and hens (White Leghorns). Some years ago, work in this laboratory required the intramuscular injection of Brown Leghorn pullets and cockerels (5 weeks of age, body-weight 500 gm.) with large doses of long-acting adrenocorticotrophin (‘Acthar’, Armour). It was found that the hormone could produce a marked rise in the level of plasma sugar in these young birds, which were kept in brooders with free access to food and water throughout the experimental period.
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