Abstract
The adrenocortical response in 18 men to acute myocardial infarction, and in 2 to myocardial ischæmia, has been studied by serial determinations of urinary 17-oxogenicsteroid, urinary " free " hydrocortisone, plasma-hydrocortisone, and two-hour post-prandial venous blood-glucose levels. The steroid levels were found to correlate with serum enzymic changes, suggesting that the magnitude of the adrenocortical response is governed by the amount of myocardial necrosis. The rise in white-blood-cell count also showed a close correlation with the steroid response.
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