Abstract

Conscious dogs were injected intravenously with 1.0mg/kg of pilocarpine or 0.3mg/kg of nicotine. Adrenal venous effluent was collected before and after the injection and analyzed for adrenaline and noradrenaline fluorimetrically. After the injection of pilocarpine a marked increase in adrenaline secretion with an inconsistent and slight increase in noradrenaline secretion was observed. Following the injection of nicotine the adrenaline and noradrenaline secretion increased markedly, the increase in the former being predominant.

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