Abstract
Boza Josipovic (Y) University of Belgrade Medical School, Institute of Rheumatology Belgrade, Yugoslavia It is well known that females suffer more frequently from rheumatoid arthritis (RA) than males, especially in the middle ages (sex ratio 4–5:1). Some of the reasons considered for that are immunostimulation by estrogen in females and, on the other hand, immunoinhibition (protection) by testosterone in males. But one can assume that function of the adrenal cortex (i.e., synthesis and secretion) of cortisol can also be altered especially in females contributing to their higher prevalence of RA and to the higher disease activity when compared to males.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
