Adrenal Myelolipoma Associated with Spherocytosis: An Extremely Rare Case

Youness Chakir​,Adil Debbagh,Rachid Aboutaieb,Jandou Issam,El Mahdi Graiouid,Mohamed Dakir

doi:10.4236/crcm.2019.811034

Abstract

Adrenal myelolipoma is a benign, non-secreting tumor composed of adipose and myeloid tissue that can be complicated by retroperitoneal pain or hemorrhage. Its diagnosis is carried by the computed tomography (CT) and confirmed histologically. Surgery may be necessary in case of large volume, symptomatic mass or complication. We report the case of a 36-year-old patient who has a combination of myelolipoma and hereditary spherocytosis, which is extremely rare in the world literature. Computed tomography guided the diagnosis and surgical excision was performed because of the volume of the mass and its symptomatic nature. The evolution at two years was without recurrences.

Highlights

Adrenal myelolipoma is a rare tumor, its first description in the literature dates from 1905, its composition is made of adipose and hematopoietic tissue [1]
Adrenal myelolipoma is a benign, non-secreting tumor composed of adipose and myeloid tissue that can be complicated by retroperitoneal pain or hemorrhage
We report the case of a 36-year-old patient who has a combination of myelolipoma and hereditary spherocytosis, which is extremely rare in the world literature

Summary

Introduction

Adrenal myelolipoma is a rare tumor, its first description in the literature dates from 1905, its composition is made of adipose and hematopoietic tissue [1]. Its diagnosis is based on a CT scan that identifies the fat percentage. These radiological aspects may lead to diagnostic confusion with kidney angiomyolipoma, lipoma, and liposarcoma, it is often unexpectedly detected [2]. Hereditary spherocytosis (HS) is characterized by increased osmotic fragility and enhanced membrane loss of red blood cells (RBC) due to defective membrane protein complexes. The majority are small and asymptomatic, giant cases are described, the association with spherocytosis is rare.

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Discussion

Conclusion