Abstract
Ganglioneuromas arc benign, differentiated tumours originating from primordial neural crest cells and situated at one end of a spectrum that includes neuroblastoma and ganglioneuroblastoma1. The incidence of ganglioneuromas is unknown but they are frequently associated with von Recklinghausen's disease. Most ganglioneuromas are located in the posterior mediastinum and retroperi-toneum. The occurrence of these tumours in the adrenal medulla is less common but presents diagnostic difficulty1,2. Adrenal ganglioneuromas occur most commonly in children and young adults. Such patients often present with paraneoplastic symptoms such as diarrhoea and hypertension3. Malignant transformation of adrenal ganglioneuromas and tumours of mixed ganglioneuroma and phaeochromocytoma have also been reported3.
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