Abstract
Adrenal cysts of epithelial origin were found incidentally in the adrenal cortical tissues of two adult female saddleback tamarins. In one case, a small cluster of minor cysts was located at the cortico-medullary border. The cysts were filled with a periodic acid-Schiff (PAS)-positive, amorphous substance and lined by a cuboidal PAS-negative epithelium, which resembled morphologically the ascending Henle's loops of the kidney. These microcysts were thought to be mesonephric remnants. In the second case, two large cysts of 1 to 3 mm diameter extended throughout the entire cortex. The cysts were filled by a watery, PAS-negative fluid and lined by a bi- to multi-layered, cytokeratin-positive epithelium. The basal epithelial layer consisted of cuboidal cells, which became cylindrical to drop-like in appearance towards the cyst lumen. The cysts closely resembled mesothelium-derived adrenal cysts in man. This is the first report of adrenal cysts in non-human primates.
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