Abstract
To study the diagnosis and treatment of adrenal cortical carcinoma. Fifteen cases of adrenal cortical carcinoma (8 functional and 7 nonfunctional) were treated surgically during the period of 1978 - 1998. They were confirmed operatively and pathologically. The functional carcinoma usually showed typical clinical features such as Cushing's syndrome, primary aldosteronism, and adrenogenital syndrome. The nonfunctional had extra-adrenal symptoms such as acute abdominal pain and hypertension. A definite diagnosis can be made by the measurements of urine 17-ketosteroid, 17-hydrosteroid, cortisol, aldosterone, CT, and B-ultrasonography. Surgical removal of the tumor is the only effective treatment. Early diagnosis of adrenal cortical carcinoma is very difficult, especially in the non-functional.
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