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Abstract
The enzymes that phosphorylate nucleosides fall into two groups on the basis of the phosphate donors and the reaction mechanism. One group, the nucleoside kinases, utilizes nucleoside triphosphates as donors in direct displacement reactions; the other group, the nucleosides phosphotransferases, catalyzes the phosphorylation reaction with nucleoside monophosphates as donors, converting the acceptor nucleoside to its monophosphate and the nucleoside monophosphate to its unphosphorylated nucleoside.
Published Version
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