Admission pulse pressure and short-term clinical outcome in patients with intracerebral and subarachnoid hemorrhage in Inner Mongolia, China

Abstract

<title/>Objective: There are currently no data on the comparison of relationship of admission pulse pressure (PP) level with short-term clinical outcome between patients with acute intracerebral hemorrhage and subarachnoid hemorrhage in the Chinese population. We studied the association between admission PP and in-hospital death or dependency in patients with acute intracerebral hemorrhage and subarachnoid hemorrhage in Inner Mongolia, China.Methods: A total of 1604 acute intracerebral hemorrhage and 156 subarachnoid hemorrhage patients were included in the present study. Blood pressure and other study variables were collected within the first 24-hours of admission. Study outcome (death or dependency) was evaluated by trained neurologists during hospitalization. The associations between admission PP and study outcome were analyzed by using multiple logistic models.Results: PP at admission was not significantly associated with study outcome in acute subarachnoid hemorrhage (P>0·05). On the other hand, PP was significantly and positively associated with odds of study outcome in acute intracerebral hemorrhage. Compared to those with PP<50 mmHg, multivariate-adjusted odds ratio (95% confidence interval) of study outcome was 1·545 (1·111, 2·148) among intracerebral hemorrhage patients with PP70 mmHg (P = 0·01).Conclusion: Increased PP was significantly and positively associated with poor short-term clinical outcome among patients with acute intracerebral hemorrhage, but not acute subarachnoid hemorrhage, in Inner Mongolia, China.