Administration périopératoire des différentes formes de vitamine D en prévention de l’hypocalcémie transitoire après thyroïdectomie totale : résultats d’une étude prospective randomisée contrôlée

Abstract

In N-glycosylation analysis of biopharmaceuticals, analytical need depends on the phase of the manufacturing process. All important glycoanalysis steps are thoroughly discussed. Carbohydrate sequencing by exoglycosidase arrays is described in conjunction with capillary electrophoresis (CE) to identify linkage and positional isomers. A possible automated workflow for N-glycosylation based on CE is outlined.