Administration of an herbal powder based on traditional Chinese veterinary medicine enhanced the fertility of Holstein dairy cows affected with retained placenta

Abstract

Herbal powder consisted of Leonurus artemisia (Laur.) S.Y. Hu F, Angelica sinensis (OLIV.) DIELS (radix), Ligusticum chuanxiong HORT (radix), Sparganium stolonif erum (Graebn.) Buch.-Ham.exJuz (radix), Curcuma zedoaria (Christm.) ROSC (radix), Cyperu srotundus Linn. (radix), and Glycyrrhiza uralensis FISCH (radix) has a high efficacy in facilitating earlier expulsion of the placenta and lowering puerperal metritis risk, and reproductive outcomes might represent the ultimate therapeutic goal of a treatment option for retained placenta in cows. This trial was carried out to further evaluate the effect of the herbal powder on the subsequent fertility of Holstein dairy cows with retained placenta. The animals were treated with herbal powder (n = 85, 0.5 g crude herb/kg bw, p.o.) once daily for 1–3 day(s) or ceftiofur hydrochloride (n = 72, 2.2 mg/kg bw, i.m.) twice daily for 3 consecutive days, and 75 cows with no clinically visible pathological conditions, given without assistance and with no retained placenta diagnosis were included into the control group. Calving-to-first-AI interval (67.2 ± 16.2 vs. 81.9 ± 28.7, p < 0.01), services per conception (1.9 ± 1.2 vs. 2.4 ± 1.7, p < 0.05), and calving-to-conception interval (101.8 ± 47.0 vs. 129.6 ± 56.6, p < 0.01) were lower in the herbal group than in ceftiofur group. Percentage of cows pregnant within 180 days postpartum was the higher in cows from the herbal group compared to cows in ceftiofur group (75.0% vs. 90.6%, p < 0.01). Additionally, the cows in the herbal group had a very similar fertility compared to the healthy controls, including calving-to-first-AI interval (67.2 ± 16.2 vs. 66.3 ± 16.9, p＞0.05), first AI conception proportion (48.2% vs. 50.6%, p＞0.05), services per conception (1.9 ± 1.2 vs. 2.0 ± 1.1, p＞0.05), percentage of cows pregnant within 180 days postpartum (90.6% vs. 93.3%, p＞0.05) and calving-to-conception interval (101.8 ± 47.0 vs. 99.0 ± 44.7, p＞0.05). Herbal powder used in this trial might have a beneficial clinical efficacy, and thus, might represent a potential effective treatment strategy to improve the subsequent fertility of dairy cows with retained placenta.