Abstract

Juvenile idiopathic arthritis (JIA) is a severe disabling disease affecting paediatric population. 507 children with JIA are monitored in Chelyabinsk region. Oligo-articular and poly-articular types of JIA are often associated with affection of eyes (uveitis). In patients resistant to traditional basic treatment (methotrexate and cyclosporine) F-alpha inhibitors are recommended. Adalimumab, approved for treatment of children older than 4 years in the Russian Federation, is a treatment of choice in patients with JIA associated with uveitis.

Highlights

  • Juvenile idiopathic arthritis (JIA) is a severe disabling disease affecting paediatric population. 507 children with JIA are monitored in Chelyabinsk region

  • Adalimumab, approved for treatment of children older than 4 years in the Russian Federation, is a treatment of choice in patients with JIA associated with uveitis

  • Mean number of joints affected by severe arthritis: 5 [3, 8] ([25; 75%])

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Summary

Introduction

Juvenile idiopathic arthritis (JIA) is a severe disabling disease affecting paediatric population. 507 children with JIA are monitored in Chelyabinsk region. Juvenile idiopathic arthritis (JIA) is a severe disabling disease affecting paediatric population. 507 children with JIA are monitored in Chelyabinsk region. Oligo-articular and poly-articular types of JIA are often associated with affection of eyes (uveitis). In patients resistant to traditional basic treatment (methotrexate and cyclosporine) F-alpha inhibitors are recommended. Adalimumab, approved for treatment of children older than 4 years in the Russian Federation, is a treatment of choice in patients with JIA associated with uveitis

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