Adjuvan Radyoterapi Alan İnvaziv Meme Kanseri Hastalarında Prognostik Faktörlerin Değerlendirilmesi

Abstract

Objective: The aim of this study is to investigate the effect of adjuvant radiotherapy applied on patients with invasive breast cancer on survival and to determine the relationship between prognostic factors and survival in patients. Introduction: Breast cancer is the most common cause of death in women between the ages of 35-55. Surgery, chemoradiotherapy, radiotherapy, hormone therapy and immunotherapy are treatment modalities applied in breast cancers. Materials and Methods: Our retrospective study included 120 patients ranging between 39 and 68 years who were admitted to Adana City Education and Research Hospital Radiation Oncology outpatient clinic between May 2016 and March 2019 and who received adjuvant radiotherapy due to invasive breast cancer. Results: Statistically significant findings were obtained between lymphovasculer invasion, human epidermal growth factor receptor 2 positivity, tumor and lymph node status and overall survival. But, no statistically significant findings could be attained between menapause status, surgical method applied, histopathological type of tumor, presence of extracapsular invasion, estrogen and progesterone hormone receptors and overall survival. Discussion: Statistically insignificant results are thought to arise from insufficient number of patients incorporated in the study, however, their effect on overall survival was exhibited. Although early diagnosis with modern imaging methods increases overall survival in breast cancer, the selection of appropriate treatments for suitable patients is crucial. Conclusion: Even though we could not specify enough statistically, we concluded that adjuvant radiotherapy positively affected survival in the light of previous studies in the literature and our observations during present study.