Adjustment of pineal melatonin and N-acetyltransferase rhythms to change from long to short photoperiod in the Djungarian hamster Phodopus sungorus.

Abstract

In the Djungarian hamster Phodopus sungorus, the daily temporal pattern of synthesis and release of pineal hormone melatonin, mainly the length of the period of elevated melatonin levels, may be involved in transferring the information on day length to the neuroendocrine-gonadal axis. The present study investigated the time course of adjustment of the rhythm in melatonin production and concentration to the change from long to short photoperiods. Adult female Djungarian hamsters, maintained on a regime of 16 h of light and 8 h of darkness per day (LD 16:8) were transferred to the LD regime 8:16 and the daily rhythms in the pineal melatonin concentration and in the pineal N-acetyltransferase activity, as an indicator of melatonin formation, were studied at various intervals following the transfer. Under LD 16:8, the nocturnal melatonin concentration was elevated for 4.8 h. After 3 days on LD 8:16, no extension of the period of high melatonin levels occurred. 2, 4 and 6 weeks after the transfer to LD 8:16, the period of elevated melatonin levels lasted for 8.1, 9.3 and 11.5 h, respectively. Extension of the melatonin pattern proceeded first predominantly into the morning hours. Only after this extension was completed, a considerable extension into the evening hours began. Extension of the N-acetyltransferase rhythm on short photoperiods proceeded in the same way as that of the melatonin rhythm. The data show that while a change in the photoperiod might be seen by hamsters within 2 weeks after the transfer to LD 8:16, the full shortening of the photoperiod might be recognized only within 6 weeks or later.(ABSTRACT TRUNCATED AT 250 WORDS)