Adjusted Intermediate and High-Risk Stratification for Prostate Cancer Is More Prognostic Than Current NCCN Risk Grouping

Abstract

Data has shown large variations in treatment outcomes for NCCN high risk patients. Trimodality therapy (androgen deprivation therapy (ADT), low dose rate brachytherapy and external beam radiation therapy) yields superior clinical results for GS 8 patients than those with GS 9-10. We investigated whether classification of GS 8 with GS 7 patients results in more useful stratification for disease prognosis.