Abstract

Based on an analysis of the technical level of equipment utilized in cryotherapy, the issue of increasing the dosing accuracy and, accordingly, ensuring accurate and uniform cooling of a biological object was identified, which required research into the issues of controlled cooling. A software for predicting the result of cryotherapy has been developed, and a range of rational parameters for supplying gas to the cabin of the installation has been determined when performing controlled cryotherapy (i.e., from 40 to 70 g/s and from −140℃ to −160℃). An experimental model of a new type of installation, which enables cryotherapy to be conducted with changes in the main parameters of the equipment in operation in a wide range of cooling gas flow temperatures from −50℃ to −160℃, free-flow velocity from 0.1 to 2 m/s, and cryotherapy time up to 420 s, has been developed and implemented. The experimental model, together with the prediction software, forms a complex system for research and controlled implementation of cryotherapy in a wide range of operating parameters. Algorithms for implementing regulated modes for various biological objects and purposes of exposure have been developed and recommendations have been provided, enabling the practical application of the proposed concept.

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