Abstract

Adipocyte precursor populations derived from rat perirenal or epididymal fat were found to be composed of clones varying in capacity for differentiation. Perirenal tissue contained a greater proportion of those clones that differentiated extensively. It is hypothesized that differences between regions and individuals in growth of adipose tissue may be due to differences in the frequency within adipocyte precursor pools of clones with unusual capacities for replication and differentiation.

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