Adhesive Polymers in Fabrication of Transdermal Drug delivery

Abstract

Transdermal drug delivery is an integral part of novel drug delivery system, which offers attractive alternatives for delivering drugs with numerous advantages. The optimization of the adhesive properties exhibits an important challenge during pharmaceutical development on the side of minimizing the uncertainty of adhesion failure in practice. Thus aspect of adhesives in transdermal, is vital parameter for fabrication design with respect to safety, efficacy and quality of transdermal drug delivery system. The advantages of drug in adhesive transdermal patches, also prevents the partial loss of active drug during process involved in manufacturing and drying of the patches. This review article covers a brief outline of various method involved in the preparation of transdermal patches, various adhesives being used commercially, assortment of adhesion parameters, and utilization of adhesion criterion, advancement and application of adhesive technology in transdermal therapy. The article also provides groundwork of recent development of adhesive based technology in transdermal along with the future aspects.