Adhesions and endometriosis: challenges in subfertility management : (An expert opinion of the ANGEL-The ANti-Adhesions in Gynaecology Expert PaneL-group).

R L De Wilde,J Alvarez,H Roman,H Brölmann,L Pawelczyk,A Di Spiezio Sardo,M Wallwiener,P Lundorff,R Campo,Y Cheong

doi:10.1007/s00404-016-4049-2

Abstract

There is molecular evidence that endometriosis has a negative impact on the ovaries, although the exact pathophysiology concerning endometriosis-associated subfertility is not known. The negative impact on the tubo-ovarian unit can be directly by distorting the anatomy, indirectly by invoking inflammation or by oxidative damage with poorer-quality oocytes. Endometriosis even seems to have a negative effect on pregnancy outcome after in vitro fertilization.

Highlights

There is molecular evidence that endometriosis has a negative impact on the ovaries, the exact pathophysiology concerning endometriosis-associated subfertility is not known
There is molecular evidence that endometriosis has a negative impact on the ovaries [4], the exact pathophysiology concerning endometriosis-associated subfertility is not known
Its recurrent nature means that repeated surgeries are often required, which leads to further adhesion formation [12]

Summary

Introduction

Abstract There is molecular evidence that endometriosis has a negative impact on the ovaries, the exact pathophysiology concerning endometriosis-associated subfertility is not known. The negative impact on the tuboovarian unit can be directly by distorting the anatomy, indirectly by invoking inflammation or by oxidative damage with poorer-quality oocytes. Belgium infertility are six to eight times more likely to have endometriosis compared to fertile women [3].

Results

Conclusion