Abstract
Abstract Various factors affecting the extent of adhesion of hydrophilic particles to polymer surfaces have been evaluated. Specifically the kinetics of adhesion, and the influence of substrate surface tension, ionic strength, pH, and surface tension of the suspending liquid medium have been investigated. In addition the role of divalent cations has been assessed. The substrates examined exhibit a wide range of wettability and the hydrophilic particles used were both fresh and glutaraldehyde-fixed human erythrocytes. The extent of particle adhesion to various polymer surfaces is also a function of solution pH and ionic strength. At a constant pH of 6 virtually no erythrocyte adhesion occurs at ionic strengths less than 0.05. Adhesion increases with increasing ionic strength and reaches a limiting plateau value at an ionic strength of approximately 0.1. The actual level of the plateau value is quite different for each polymer. Particle adhesion is also pH dependent. For conditions of constant ionic strengt...
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