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Abstract
ABSTRACT Adherence to Treatment of Anemia with Microencapsulated Ferrous Fumarate Objective: To evaluate the adherence to treatment of anemia through the percentage of response withferrous fumarate, in comparison to ferrous sulfate drops after two months of treatment. Study Design:randomized controlled clinical trial. Intervention: ferrous sulfate drops and microencapsulated ferrousfumarate sprinkles. Methods: 128 Children (age 6-24 months) were enrolled and randomized to ferroussulfate drops group or ferrous fumarate group. Capillary blood samples taken at the baseline and final visitswere obtained from a finger prick in order to asses hemoglobin values. Compliance was also measured. Results: Successful treatment of anemia (hemoglobin > 13,6 g/dl) occurred in 54% of the sprinkles groupand in 22% of the drops group (p < 0,05). The positive response to treatment was higher in the experimentalgroup (91%) than the control group (71%) (p < 0,05). The rate of compliance was 55% in the control groupand 76% in the experimental group. The mean hemoglobin levels increases significantly in each group frombaseline to the final visit.
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