Adherence to non-invasive positive airway pressure therapy

Abstract

<b>Introduction:</b> Studies have shown very different adherence to non-invasive positive airway pressure(nPAP) therapy. We aimed to investigate the adherence to nPAP therapy in patients with chronic respiratory insufficiency due to neuromuscular disorders(NMD), obesity-hypoventilation syndrome(OHS) or other reasons to sleep-disordered breathing(SDB) in the East of Denmark. <b>Methods:</b> This cohort study included adult patients with association to the Respiratory Centre of the East of Denmark treated with nPAP therapy: bilevel(bipap), continuous(cpap) or adaptive servo-ventilation(ASV) with a&nbsp;remote monitoring system in April2022. Primary outcome was the number of adherent patients defined as median use of nPAP therapy &gt;4hours/day. <b>Results:</b> A total of 241 patients were included in the study. The number of&nbsp;adherent patients&nbsp;with OHS was 56(64%), with NMD 97(75%) including dystrophia myotonica 3(27%) and with SDB,other 21(84%). <b>Conclusion:</b> The proportion of patients that used nPAP therapy for more than 4 hrs per day was 73% in a danish population of adult patients with NMD, OHS and with&nbsp;other reasons to SDB. There were&nbsp;big&nbsp;differences in the&nbsp;proportions of adherent patients between the diagnoses.