Adherence of Option B+ prevention of mother-to-child transmission program and its associated factors among pregnant and lactating mothers in public health facilities of East Gojjam zone, Amhara region, Ethiopia, 2017

Abstract

<p class="abstract"><strong>Background:</strong> Adherence of antiretroviral treatment (ART) among women on prevention of mother-to-child transmission (PMTCT) program is a central component to reduce viral loads and achieve elimination of mother to child transmission of human immunodeficiency virus (HIV) to Ethiopia. Option B+ PMTCT program is a recently introduced approach to eliminate new HIV infection among child. There is limited evidence on the drug adherence of women on ART in the Option B+ strategy. The aim was to assess adherence of Option B+ PMTCT drug and its associated factors among pregnant & lactating mothers in health facilities of East Gojjam zone, Amhara, Ethiopia, 2017.</p><p class="abstract"><strong>Methods:</strong> Institution based cross-sectional study design was conducted from randomly selected three public health facilities in East Gojjam zone. Data was entered in to Epi data 3.1 and cleared then transferred to SPSS version 20 for analysis. To assess the associated factors, logistic regression model was employed. A p value <0.05 was considered statistically significant. </p><p class="abstract"><strong>Results:</strong> Adherence on Option B+ PMTCT drug was 75%. The likelihood of being adherence found to be significant association with the following variables: Mother’s educational status (AOR=2.03; 95%CI: 1.465, 8.918), partner occupation (AOR=4.73; 95%CI: 1.12, 19.87), time to reach to health facility (AOR=0.21; 95%CI: 0.05, 0.824), and maternal HIV knowledge (AOR=0.13; 95%CI: 0.03, 0.44).</p><strong>Conclusions:</strong> Adherence to Option B+ PMTCT drug in East Gojjam zone, Amhara region was low compared to the national goal. Effort should be made both governmentally as well as non- governmentally to advance the knowledge about Option B+ PMTCT program so as to improve the long term maternal and child health.