Adenovirus Proteins and Their Messenger RNAs

Abstract

Publisher Summary This chapter discusses recent results concerning early and late adenovirus messenger RNAs and proteins. An emphasis on their map positions on the viral genome and their possible function in early and late virus gene expression is considered appropriate. An attempt to review available data on adenovirus assembly is also included. The chapter focuses on gene expression of the group C human adenoviruses comprising the thoroughly studied types ad2 and ad5. Similar, but not identical, results have been reported for other human and avian adenoviruses but in most cases, the human group C adenoviruses have been studied in more detail at the molecular level. The chapter concludes that delineation of the molecular events occurring at both the initiation of DNA replication and transcription in a mammalian cell will be forthcoming.