Abstract
This article reports the relationship between prenatal respiratory infections such as human respiratory adenovirus (HRAV) and/or human respiratory syncytial virus (HRSV) and orofacial clefts (OFC). Specific antibodies against HRAV and HRSV were investigated serologically (ELISA) in newborns with orofacial cleft and their mothers. The results were compared with those obtained from healthy newborns (controls) and their mothers. Statistical evaluation revealed significant changes in HRAV IgA antibodies between mothers of children with OFC and mothers with healthy newborns. HRSV antibodies of newborns with OFC were changed only marginaly (p = 0.0665) compared to controls. Our results indicate possible involvement of HRSV and HRAV in congenital orofacial defects, however these results have to be confirmed in larger scale study.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
