Adenotonsillectomy: Effect on CRP Level in Children

Abstract

There is an increased risk of cardiovascular and cerebrovascular events in patients with obstructive sleep apnea (OSA). There are contradictory results about the correlation between serum CRP levels and OSA severity. The purpose of this work was to evaluate CRP level after adenotonsillectomy in children with clinical symptoms, suspected OSA. This cross – sectional study was conducted between 20 March 2012 and 20 November 2014. The study group was composed of 98 children that indicated adenotonsillectomy due to clinical symptom of OSA. CRP were measured before and after surgery. Of total 98 children (52 males and 46 females) with an average age of 8.14 ± 2.6 years, 14(14.3%), 29(29.6%), 44(44.9%), and 11(11.2%) patients were with adenoid grade I, II, III, and IV, respectively and in aspect of tonsil grade, 8(8.2%) with grade I, 37(37.8%) with grade II, 43(43.9%) with grade III, and 10(10.1%) were with grade IV. Comparison of the mean of CRP before and after surgery, based on preoperative adenoid grade showed a significant difference in grade III and IV before and after surgery. In aspect of tonsil grade, in grade I, II and III, the mean CRP before and after surgery showed significant difference too. We found that change of CRP level has relationship with the grade of adenoid and tonsil hypertrophy, and may be helpful marker for indication of adenotonsillectomy.