Abstract
Abstract Adenosquamous carcinoma (ASC) of the esophagus is an uncommon primary esophageal malignancy of uncertain pathogenesis, with several challenges complicating the establishment of a correct diagnosis. Neither the natural history nor the prognostic and therapeutic implications are well understood for this tumor. We report a case of a 71-year-old man who was found to have an ASC at the gastrointestinal junction. The clinicopathologic features as well as what is known of the epidemiology, pathogenesis, and prognosis and treatment of ASC are discussed, along with other possible coexisting disease.
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